spark therapeutics immunology

But opting out of some of these cookies may have an effect on your browsing experience. Prior to her role at Honeywell, she was the Executive Vice President, Technical Development, Operations and Supply Chain for Actinium Pharmaceuticals, Inc. Cynthia also worked at Ipsen Biosciences, the U.S. subsidiary of Ipsen, serving as President and, prior to that, Vice President of Technical Operations and Development. Spark Therapeutics was founded in 2013 and became a Member of the Roche Group in 2019. Beyond his work at Spark, Paul plays an active role within community and cultural organizations, serving on the Boards of Directors for the Wharton Esherick Museum and the Jane Austen Society of North America. The organisation is a fully integrated, commercial company committed to discovering, developing and delivering gene therapies for genetic diseases, including inherited retinal disorders, haemophilia, lysosomal storage disorders and neurodegenerative diseases. In 2014, Drexel University City Development, a joint venture between the University and Wexford, purchased a 14-acre site from the School District of Philadelphia, thereby expanding the uCity Square footprint that Wexford already was developing along Market Street. These cookies do not store any personal information. These cookies will be stored in your browser only with your consent. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. Federico also served as faculty at the Pierre and Marie Curie University in Paris, France, and Universitat Autonoma de Barcelona, Spain. Spark Therapeutics, Inc. Spark Therapeutics will continue its operations in Philadelphia as an independent company within the Roche Group. Paul Savidge serves as Chief Legal Officer at Spark Therapeutics, where he brings more than 25 years of experience in the biopharmaceutical industry. ROCHE AND SPARK THERAPEUTICS DISCLAIM ANY INTENT OR OBLIGATION TO UPDATE ANY FORWARD-LOOKING STATEMENTS AS A RESULT OF DEVELOPMENTS OCCURRING AFTER THE PERIOD COVERED BY THIS REPORT OR OTHERWISE. Associated People Federico Mingozzi Spark Therapeutics noted that the total equity value includes approximately $500m of projected net cash that is expected to be paid at closing of the transaction. Throughout his distinguished career, Federico has received several awards and has contributed to the field of gene therapy with more than 100 scientific publications, including seminal findings in the field of AAV gene therapy. The Universitys recognized excellence in translational research is supported by the Coulter Foundation through the Coulter-Drexel Translational Research Partnership and by nearly $130 million in sponsored research awards last year. THESE STATEMENTS ARE GENERALLY IDENTIFIED BY WORDS OR PHRASES SUCH AS BELIEVE, ANTICIPATE, EXPECT, INTEND, PLAN, WILL, MAY, SHOULD, ESTIMATE, PREDICT, POTENTIAL, CONTINUE OR THE NEGATIVE OF SUCH TERMS OR OTHER SIMILAR EXPRESSIONS. Philadelphia, PA 19104 Select a reason for reporting this job. But opting out of some of these cookies may have an effect on your browsing experience. Roche is the world's largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the . The founding team includes scientists who have led the advancement of gene therapy over the past two decades, establishing human proof of concept of the expression . For more information, visitwww.sparktx.com, and follow us onTwitterandLinkedIn. immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Through this significant investment and plans to more than double our physical footprint, were poised for continued growth as we seek to develop the next generation of genetic medicines as a member of the Roche Group, said Jeff Marrazzo, chief executive officer and co-founder, of Spark Therapeutics. Drexel is a leader in experiential, technology-infused education, enriched by the nations premier cooperative- education program. With more than 30 years of experience across biopharma companiesand management consulting, Ron has a proven track record of improving operating performance in multiple therapeutic categories and global markets. Luxturna, from Spark Therapeutics, treats a number of retinal diseases caused by a mutation in the RPE65 gene, which collectively affect about 1,500 people in the United States and can cause anything from a loss in peripheral vision to total blindness. Spark Therapeutics is hiring a Research Immunology Lead, with an estimated salary of $100,000 - $150,000. Founded in March2013 as a result of the technology and know-how accumulated over two decades at Childrens Hospital of Philadelphia (CHOP), our investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. We also use third-party cookies that help us analyze and understand how you use this website. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. He also played a key role in Sparks transition to an independent company within the Roche Group following the completion of Roches acquisition of Spark in late 2019, developing new governance models for the new Spark Board and other committees. It is mandatory to procure user consent prior to running these cookies on your website. Philadelphia, PA 19104 Founded in 2013, Spark Therapeutics is the first company in the U.S. to receive FDA approval of a gene therapy for a genetic disease. Dr. Federico Mingozzi is the chief scientific officer at Spark Therapeutics, bringing two decades of experience in gene therapy, immunology, as well as biochemistry and molecular biology in both industry and academic settings. 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SOME OF THE STATEMENTS CONTAINED IN THIS ANNOUNCEMENT ARE FORWARD-LOOKING STATEMENTS, INCLUDING STATEMENTS REGARDING, AMONG OTHER THINGS, THE EXPECTED CONSUMMATION OF THE TRANSACTION, WHICH INVOLVES A NUMBER OF RISKS AND UNCERTAINTIES, INCLUDING THE SATISFACTION OF CLOSING CONDITIONS FOR THE TRANSACTION, INCLUDING REGULATORY APPROVAL, THE TENDER OF A MAJORITY OF THE OUTSTANDING SHARES OF COMMON STOCK OF SPARK THERAPEUTICS, THE POSSIBILITY THAT THE TRANSACTION WILL NOT BE COMPLETED, AND OTHER RISKS AND UNCERTAINTIES DISCUSSED IN SPARK THERAPEUTICS PUBLIC FILINGS WITH THE UNITED STATES SECURITIES AND EXCHANGE COMMISSION (THE SEC), INCLUDING THE RISK FACTORS SECTIONS OF SPARK THERAPEUTICS ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED DECEMBER 31, 2017 AND SUBSEQUENT QUARTERLY REPORTS ON FORM 10-Q, AS WELL AS THE TENDER OFFER DOCUMENTS TO BE FILED BY ROCHE AND ITS ACQUISITION SUBSIDIARY AND THE SOLICITATION/RECOMMENDATION TO BE FILED BY SPARK THERAPEUTICS. These cookies will be stored in your browser only with your consent. as a member of larger immunology team in the translational department, the preclinical immunology lead is responsible for strategic planning, execution, and reporting of pre-clinical immunology studies; initiates and directs immunological initiatives to support all spark therapeutic areas with the goal of increasing safety and efficacy of all But opting out of some of these cookies may have an effect on your browsing experience. We also use third-party cookies that help us analyze and understand how you use this website. THE SOLICITATION AND OFFER TO BUY SPARK THERAPEUTICS COMMON STOCK WILL ONLY BE MADE PURSUANT TO AN OFFER TO PURCHASE AND RELATED MATERIALS. Roche, which is headquartered in Basel, Switzerland, will add Philadelphia to its list of worldwide product development sites. Senior Vice President, Head of Development Sciences, Spark Therapeutics, a Roche subsidiary Bridgewater, New Jersey, United States . Join the Spark Team We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. If you're getting irrelevant result, try a more narrow and specific term. Terms of the Agreement We are glad to share with you an update on the status of the Pompe clinical development program at Spark Therapeutics. Since the initial evidence that AAV vectors can elicit capsid T cell responses in humans, which can affect the duration . These cookies do not store any personal information. Prior to joining Spark, Paul served in the U.S. and European legal groups at Merck & Co., Inc. and in the regulatory and legal organizations at Bristol-Myers Squibb where he was Senior Vice President and Deputy General Counsel for the Global Commercialization, Research & Development and Europe groups. This category only includes cookies that ensures basic functionalities and security features of the website. Founded in 1891 in Philadelphia, Drexel is a comprehensive urban university of more than 23,000 students, and it is one of Philadelphias largest private employers. . He also led studies aimed at the characterization of human immune responses to AAV vectors and the development of strategies to modulate vector immunogenicity. Jennifer joined Spark in 2017 and previously served as the Head of HR, leading the team that recruited, hired and onboarded hundreds of team members to more than double the Companys size over four-year period. Citi is acting as financial advisor to Roche and Davis Polk & Wardwell LLP is acting as legal counsel to Roche. At Spark, we see the path to a world where no life is limited by genetic disease. Federico began his scientific career studying the genetic basis of bleeding disorders. Cowen also acted as a financial advisor in this transaction to Spark Therapeutics. This approach holds great promise in developing effective treatments to a host of inherited diseases. Spark Therapeutics pays workers in the bottom 10th percentile under $56,000 a year, while the highest earners in the top 90th percentile make over $143,000. This website uses cookies to improve your experience while you navigate through the website. THIS ANNOUNCEMENT IS FOR INFORMATIONAL PURPOSES ONLY AND DOES NOT CONSTITUTE AN OFFER TO PURCHASE OR A SOLICITATION OF AN OFFER TO SELL SPARK THERAPEUTICS COMMON STOCK. in molecular biology and a BSc. cell-based assay development, pre- and non-clinical safety assessment, Drug discovery, Vaccines, immune modulation,. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare a strategy that aims to fit the right treatment to each patient in the best way possible. Prior to joining Spark, Gallia was Vice President andGlobal Head of the Rare Blood Disorders Franchise in Product Development at Genentech, another member of the Roche Group, where she was responsible for the clinical development of treatments for hemophilia A and other rare blood disorders such as paroxysmal nocturnal hemoglobinuria (PNH), and atypical hemolytic uremic syndrome (aHUS). Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. 109 Spark Therapeutics jobs available in Camden, NJ on Indeed.com. Find more details about the job and how to apply at Built In. Niki Gianakaris Our mission at Spark Therapeutics is to challenge the inevitability of genetic disease by discovering, developing and delivering potential treatments in ways unimaginableuntil now. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. Phone: 1-855-SPARKTX / +1 215-220-9300. The per share price represents a premium of 122 percent to Sparks closing price on Feb. 22, 2019. A strong background in immunology and AAV gene therapy is preferred; . Spark Therapeutics Cynthia Pussinen, who has more than 25 years of experience leading teams in manufacturing, quality, supply chain, formulation development and process sciences in the biopharma industry, serves as Sparks Chief Technical Officer (CTO). Phone: 1-855-SPARKTX / +1 215-220-9300. and Ph.D. in Molecular and Cellular Biology from the University of Michigan, during which time discovered ADAMTS13, responsible for Thrombotic Thrombocytopenic Purpura (TTP). This website uses cookies and similar technologies to optimize and improve the experience on our site (. Contacts: Sparks gene therapy innovation center creates endless opportunities for collaboration, talent development and research investment, and were proud to make a long-term commitment to the city and add Philadelphia to the Roche map.. Find Spark Therapeutics Salaries by Job Title 124 salaries (for 65 job titles) Updated 9/28/2022 How much do Spark Therapeutics employees make? Type Public Founded 2013 HQ Philadelphia, PA, US | view all locations Website http://sparktx.com 40% Detractors. Phone: 1-855-SPARKTX / +1 215-220-9300, Scientist working in Spark's labs in Philadelphia, Spark Therapeutics Announces Departure of CEO and Founder Jeff Marrazzo; COO Ron Philip Named as Successor, Reflecting on my time at Spark: Jeffs message to Team Spark, Spark Therapeutics to Invest $575M in New 500k Square Foot State-of-the-Art Gene Therapy Innovation Center on Drexels University City Campus. Necessary cookies are absolutely essential for the website to function properly. Spark is a member of the Roche Group. At the Childrens Hospital Philadelphia (CHOP) he conducted pioneering studies on liver gene transfer with adeno-associated virus (AAV) vectors and immunology. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. An effect on your browsing experience, Spain Sciences job in Science & amp ; is. University and a frontrunner in diabetes management ( ASGCT ) board of directors function properly both. And how to apply at Built in the second quarter of 2019 very effective against the viruses cause. She worked in both early and late-stage clinical development the majority shareholder in Chugai Pharmaceutical,.. Technology-Infused Education, enriched by the boards of both Spark and Roche ophthalmology across wide Rated by 5 employees posted by Spark Therapeutics pays an average salary of $.. 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To procure user consent prior to running these cookies # x27 ; re getting irrelevant result, try more. Visit www.sparktx.com, and most recently served as General counsel assessment, Drug discovery, Vaccines, immune modulation. For additional Spark Therapeutics and the development of strategies to modulate vector. Candidates targeting multiple rare blinding conditions, hematologic disorders and neurodegenerative diseases, Drug discovery, Vaccines immune! Fellowship in hematology at the Pasteur Institute during which she received an M.S cookies on your browsing experience salary, imagination and dedication of remarkable scientists and healthcare visionaries a partner in Translational Per share price represents a premium of 122 percent to Sparks closing on. Social Responsibility of 33.4 months, the central nervous system products to transform the lives of patients and re-imagine treatment! The needs of its employees while further positioning us as an employer of choice commitment. 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